The duo go all out for laughs in the wild debut footage.

Eric André is John Cena’s Little Brother from hell in first trailer for bonkers Netflix comedy

The duo go all out for laughs in the wild debut footage.

By Derek Lawrence

Derek Lawrence

Derek Lawrence is a former associate editor at **. He left EW in 2022.

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May 20, 2026 8:00 a.m. ET

John Cena and Eric André in 'Little Brother'. Credit:

Clifton Prescod/Netflix

- Netflix has released the first trailer for the new comedy *Little Brother*.

- John Cena and Eric André are reunited after a memorable interaction on* The Eric André Show*.

- The film premieres June 26 on the streaming platform.

The trailer for Netflix's *Little Brother* has John Cena wishing he were an only child.

The raunchy first footage puts both Cena and Eric André through the wringer as their characters change each other's lives, for better or worse.

When alerted that his brother was in an accident, Rudd (Cena) and his wife, Deirdre (Michelle Monaghan), rush to the hospital, assuming Rudd's big bro Josh (Christopher Meloni) has been injured. Instead, he finds André's eccentric — and possibly mentally unstable —Marcus. "Who the f--- is this?" Rudd asks.

It turns out that Marcus was Rudd's "little brother" in a Big Brother-like program in high school, and they haven't spoken since. But with Marcus having nowhere else to go, Dierdre convinces Rudd to bring him home. NSFW chaos ensues.

Directed by Matt Spicer (*Ingrid Goes West*) and written by Jarrad Paul and Andrew Mogel, André described the film to EW as "*What About Bob?* meets *Parasite*."

"I think it's a movie that all audiences can relate to," Cena shared. "We try so hard to create our own perfect environment, and in short, this movie is exactly what happens when you get your environment absolutely perfect, and then you encounter a s--- storm."

Eric André blows up John Cena's life — and teaches the 'ancient art of analingus' — in 'Little Brother' first look

'Blockers' star John Cena is ready to make you forget he's John Cena

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The cast also includes comedy scene-stealers like Ego Nwodim (*Saturday Night Live*), Sherry Cola (*Shrinking*), and Caleb Hearon (*The Devil Wears Prada 2*).

*Little Brother* premieres June 26 on Netflix.

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Source: “EW Comedy”